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Modulation of the kappa and mu opioid axis for the treatment of chronic pruritus: A review of basic science and clinical implications
INTRODUCTION: Treating chronic pruritus is challenging for dermatologists due to the lack of therapeutic options. We review the effects of κ-opioid receptor (KOR) and μ-opioid receptor (MOR) in the modulation of itch, summarize evidence supporting the efficacy and safety of opioid receptor–targeting...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046882/ https://www.ncbi.nlm.nih.gov/pubmed/35497636 http://dx.doi.org/10.1016/j.jdin.2022.03.007 |