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Modulation of the kappa and mu opioid axis for the treatment of chronic pruritus: A review of basic science and clinical implications

INTRODUCTION: Treating chronic pruritus is challenging for dermatologists due to the lack of therapeutic options. We review the effects of κ-opioid receptor (KOR) and μ-opioid receptor (MOR) in the modulation of itch, summarize evidence supporting the efficacy and safety of opioid receptor–targeting...

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Detalles Bibliográficos
Autores principales:	Elmariah, Sarina, Chisolm, Sarah, Sciascia, Thomas, Kwatra, Shawn G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046882/ https://www.ncbi.nlm.nih.gov/pubmed/35497636 http://dx.doi.org/10.1016/j.jdin.2022.03.007

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