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Mechanistic insights into multiple-step transport of mitochondrial ADP/ATP carrier

The ADP/ATP carrier (AAC) is crucial for mitochondrial functions by importing ADP and exporting ATP across the inner mitochondrial membrane. However, the mechanism of highly specific ADP recognition and transport by AAC remains largely elusive. In this work, spontaneous ADP binding process to the gr...

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Detalles Bibliográficos
Autores principales: Yao, Shihao, Yi, Qiuzi, Ma, Boyuan, Mao, Xiaoting, Chen, Ye, Guan, Min-Xin, Cang, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046947/
https://www.ncbi.nlm.nih.gov/pubmed/35521544
http://dx.doi.org/10.1016/j.csbj.2022.03.032