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Maternal obesogenic diet enhances cholestatic liver disease in offspring

Human and animal model data show that maternal obesity promotes nonalcoholic fatty liver disease in offspring and alters bile acid (BA) homeostasis. Here we investigated whether offspring exposed to maternal obesogenic diets exhibited greater cholestatic injury. We fed female C57Bl6 mice conventiona...

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Detalles Bibliográficos
Autores principales: Thompson, Michael D., Hinrichs, Holly, Faerber, Austin, Tarr, Phillip I., Davidson, Nicholas O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046959/
https://www.ncbi.nlm.nih.gov/pubmed/35341737
http://dx.doi.org/10.1016/j.jlr.2022.100205