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Chk1 Inhibition Hinders the Restoration of H3.1K56 and H3.3K56 Acetylation and Reprograms Gene Transcription After DNA Damage Repair

H3K56 acetylation (H3K56Ac) was reported to play a critical role in chromatin assembly; thus, H3K56ac participates in the regulation of DNA replication, cell cycle progression, DNA repair, and transcriptional activation. To investigate the influence of DNA damage regulators on the acetylation of his...

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Detalles Bibliográficos
Autores principales: Ding, Nan, Shao, Zhiang, Yuan, Fangyun, Qu, Pei, Li, Ping, Lu, Dong, Wang, Jufang, Zhu, Qianzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046994/
https://www.ncbi.nlm.nih.gov/pubmed/35494003
http://dx.doi.org/10.3389/fonc.2022.862592