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Synthesis of (124)I-labeled epichaperome probes and assessment in visualizing pathologic protein-protein interaction networks in tumor bearing mice

Epichaperomes are disease-associated pathologic scaffolds composed of tightly bound chaperones and co-chaperones. They provide opportunities for precision medicine where aberrant protein-protein interaction networks, rather than a single protein, are detected and targeted. This protocol describes th...

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Detalles Bibliográficos
Autores principales: Sharma, Sahil, Kalidindi, Teja, Joshi, Suhasini, Digwal, Chander S., Panchal, Palak, Burnazi, Eva, Lee, Sang Gyu, Pillarsetty, Nagavarakishore, Chiosis, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046997/
https://www.ncbi.nlm.nih.gov/pubmed/35496791
http://dx.doi.org/10.1016/j.xpro.2022.101318