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Celecoxib induces adipogenic differentiation of hemangioma-derived mesenchymal stem cells through the PPAR-γ pathway in vitro and in vivo

Infantile hemangioma (IH) is a benign tumor that produces a permanent scar or a mass of fibro-fatty tissue after involution in 40-80% of cases. Celecoxib is an inhibitor of cyclooxygenase-2 (COX-2), and can inhibit angiogenesis and fibrosis. The present study aimed to clarify whether celecoxib is ab...

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Detalles Bibliográficos
Autores principales: Wang, Yuan, Kong, Liangliang, Sun, Buhao, Cui, Jie, Shen, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047034/
https://www.ncbi.nlm.nih.gov/pubmed/35495586
http://dx.doi.org/10.3892/etm.2022.11303