Multifaceted Activities of Seven Nanobodies against Complement C4b

Cleavage of the mammalian plasma protein C4 into C4b initiates opsonization, lysis, and clearance of microbes and damaged host cells by the classical and lectin pathways of the complement system. Dysregulated activation of C4 and other initial components of the classical pathway may cause or aggrava...

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Detalles Bibliográficos
Autores principales: De la O Becerra, Karla I., Oosterheert, Wout, van den Bos, Ramon M., Xenaki, Katerina T., Lorent, Joseph H., Ruyken, Maartje, Schouten, Arie, Rooijakkers, Suzan H. M., van Bergen en Henegouwen, Paul M. P., Gros, Piet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2022
Materias:
Molecular and Structural Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047069/
https://www.ncbi.nlm.nih.gov/pubmed/35428691
http://dx.doi.org/10.4049/jimmunol.2100647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047069/
https://www.ncbi.nlm.nih.gov/pubmed/35428691
http://dx.doi.org/10.4049/jimmunol.2100647

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