Functional interaction between endothelin-1 and ZEB1/YAP signaling regulates cellular plasticity and metastasis in high-grade serous ovarian cancer

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) encompasses a highly dynamic and complex key process which leads to metastatic progression. In high-grade serous ovarian carcinoma (HG-SOC), endothelin-1 (ET-1)/endothelin A receptor (ET(A)R) signaling promotes EMT driving tumor progression. How...

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Detalles Bibliográficos
Autores principales: Sestito, Rosanna, Tocci, Piera, Roman, Celia, Di Castro, Valeriana, Bagnato, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047299/
https://www.ncbi.nlm.nih.gov/pubmed/35477522
http://dx.doi.org/10.1186/s13046-022-02317-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047299/
https://www.ncbi.nlm.nih.gov/pubmed/35477522
http://dx.doi.org/10.1186/s13046-022-02317-1

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