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Functional interaction between endothelin-1 and ZEB1/YAP signaling regulates cellular plasticity and metastasis in high-grade serous ovarian cancer

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) encompasses a highly dynamic and complex key process which leads to metastatic progression. In high-grade serous ovarian carcinoma (HG-SOC), endothelin-1 (ET-1)/endothelin A receptor (ET(A)R) signaling promotes EMT driving tumor progression. How...

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Detalles Bibliográficos
Autores principales:	Sestito, Rosanna, Tocci, Piera, Roman, Celia, Di Castro, Valeriana, Bagnato, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047299/ https://www.ncbi.nlm.nih.gov/pubmed/35477522 http://dx.doi.org/10.1186/s13046-022-02317-1

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