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Predicting male fertility from the sperm methylome: application to 120 bulls with hundreds of artificial insemination records

BACKGROUND: Conflicting results regarding alterations to sperm DNA methylation in cases of spermatogenesis defects, male infertility and poor developmental outcomes have been reported in humans. Bulls used for artificial insemination represent a relevant model in this field, as the broad disseminati...

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Detalles Bibliográficos
Autores principales: Costes, Valentin, Chaulot-Talmon, Aurélie, Sellem, Eli, Perrier, Jean-Philippe, Aubert-Frambourg, Anne, Jouneau, Luc, Pontlevoy, Charline, Hozé, Chris, Fritz, Sébastien, Boussaha, Mekki, Le Danvic, Chrystelle, Sanchez, Marie-Pierre, Boichard, Didier, Schibler, Laurent, Jammes, Hélène, Jaffrézic, Florence, Kiefer, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047354/
https://www.ncbi.nlm.nih.gov/pubmed/35477426
http://dx.doi.org/10.1186/s13148-022-01275-x