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Predicting male fertility from the sperm methylome: application to 120 bulls with hundreds of artificial insemination records
BACKGROUND: Conflicting results regarding alterations to sperm DNA methylation in cases of spermatogenesis defects, male infertility and poor developmental outcomes have been reported in humans. Bulls used for artificial insemination represent a relevant model in this field, as the broad disseminati...
Autores principales: | Costes, Valentin, Chaulot-Talmon, Aurélie, Sellem, Eli, Perrier, Jean-Philippe, Aubert-Frambourg, Anne, Jouneau, Luc, Pontlevoy, Charline, Hozé, Chris, Fritz, Sébastien, Boussaha, Mekki, Le Danvic, Chrystelle, Sanchez, Marie-Pierre, Boichard, Didier, Schibler, Laurent, Jammes, Hélène, Jaffrézic, Florence, Kiefer, Hélène |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047354/ https://www.ncbi.nlm.nih.gov/pubmed/35477426 http://dx.doi.org/10.1186/s13148-022-01275-x |
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