Cargando…

A centrifugation-assisted visual detection of SNP in circulating tumor DNA using gold nanoparticles coupled with isothermal amplification

Detection of single-nucleotide polymorphism (SNP) in circulating tumor DNA (ctDNA) is challenging because of the large DNA fragmentation (∼150 nt) and the strong background of normal cell free DNA (cfDNA). Here we developed a rapid centrifugation-assisted colorimetric assay using gold nanoparticles...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yusong, Kong, Say Li, Su, Xiao Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047361/
https://www.ncbi.nlm.nih.gov/pubmed/35494678
http://dx.doi.org/10.1039/c9ra09029k