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Discovery of genes positively modulating treatment effect using potential outcome framework and Bayesian update
BACKGROUND: The recent explosion of cancer genomics provides extensive information about mutations and gene expression changes in cancer. However, most of the identified gene mutations are not clinically utilized. It remains uncertain whether the presence of a certain genetic alteration will affect...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047392/ https://www.ncbi.nlm.nih.gov/pubmed/35477453 http://dx.doi.org/10.1186/s12911-022-01852-3 |