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Betulin Targets Lipin1/2-Meidated P2X7 Receptor as a Therapeutic Approach to Attenuate Lipid Accumulation and Metaflammation

The present study focused on the potential mechanism of betulin (BT), a pentacyclic triterpenoid isolated from the bark of white birch (Betula pubescens), against chronic alcohol-induced lipid accumulation and metaflammation. AML-12 and RAW 264.7 cells were administered ethanol (EtOH), lipopolysacch...

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Detalles Bibliográficos
Autores principales: Dou, Jia-Yi, Jiang, Yu-Chen, Hu, Zhong-He, Yao, Kun-Chen, Yuan, Ming-Hui, Bao, Xiao-Xue, Zhou, Mei-Jie, Liu, Yue, Li, Zhao-Xu, Lian, Li-Hua, Nan, Ji-Xing, Wu, Yan-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047492/
https://www.ncbi.nlm.nih.gov/pubmed/34815367
http://dx.doi.org/10.4062/biomolther.2021.136