The Endoplasmic Reticulum Stress Response Mediates Shikonin-Induced Apoptosis of 5-Fluorouracil–Resistant Colorectal Cancer Cells

Resistance to chemotherapeutic drugs is a significant problem in the treatment of colorectal cancer, resulting in low response rates and decreased survival. Recent studies have shown that shikonin, a naphthoquinone derivative, promotes apoptosis in colon cancer cells and cisplatin-resistant ovarian...

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Detalles Bibliográficos
Autores principales: Piao, Mei Jing, Han, Xia, Kang, Kyoung Ah, Fernando, Pincha Devage Sameera Madushan, Herath, Herath Mudiyanselage Udari Lakmini, Hyun, Jin Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047496/
https://www.ncbi.nlm.nih.gov/pubmed/34607978
http://dx.doi.org/10.4062/biomolther.2021.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047496/
https://www.ncbi.nlm.nih.gov/pubmed/34607978
http://dx.doi.org/10.4062/biomolther.2021.118

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