Stereodivergent access to all four stereoisomers of chiral tetrahydrobenzo[f][1,4]oxazepines, through highly diastereoselective multicomponent Ugi–Joullié reaction

Starting from easily accessible chiral enantiopure 1,2-amino alcohols and salicylaldehydes, a concise route to cyclic imines has been developed. These chiral cyclic imines undergo a highly diastereoselective Ugi–Joullié reaction to give trans tetrahydrobenzo[f][1,4]oxazepines with the introduction o...

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Detalles Bibliográficos
Autores principales: Pinna, Alessandro, Basso, Andrea, Lambruschini, Chiara, Moni, Lisa, Riva, Renata, Rocca, Valeria, Banfi, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047508/
https://www.ncbi.nlm.nih.gov/pubmed/35494435
http://dx.doi.org/10.1039/c9ra10689h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047508/
https://www.ncbi.nlm.nih.gov/pubmed/35494435
http://dx.doi.org/10.1039/c9ra10689h

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