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Efficient synthesis of 4-sulfanylcoumarins from 3-bromo-coumarins via a highly selective DABCO-mediated one-pot thia-Michael addition/elimination process

A facile and efficient protocol for the highly selective direct sulfanylation of 3-bromocoumarins under DABCO promotion, was developed. The transformation took place with aromatic and aliphatic thiols as well as with α,ω-dithiols, affording the expected products in very good to excellent yields. Sim...

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Detalles Bibliográficos
Autores principales: Mostardeiro, Vitor B., Dilelio, Marina C., Kaufman, Teodoro S., Silveira, Claudio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047558/
https://www.ncbi.nlm.nih.gov/pubmed/35492534
http://dx.doi.org/10.1039/c9ra09545d