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Combination of Vitamin C and Curcumin Safeguards Against Methotrexate-Induced Acute Liver Injury in Mice by Synergistic Antioxidant Effects

Methotrexate (MTX), an antineoplastic and immunosuppressive drug, widely used in the treatment of different types of cancers and the management of chronic inflammatory diseases. However, its use is associated with hepatotoxicity. Vitamin C (VC) and curcumin (CUR) exhibit anti-inflammatory and antiox...

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Detalles Bibliográficos
Autores principales: Hasan Khudhair, Dhekra, Al-Gareeb, Ali I., Al-kuraishy, Hayder M., El-Kadem, Aya H., Elekhnawy, Engy, Negm, Walaa A., Saber, Sameh, Cavalu, Simona, Tirla, Adrian, Alotaibi, Saqer S., Batiha, Gaber El-Saber
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047671/
https://www.ncbi.nlm.nih.gov/pubmed/35492324
http://dx.doi.org/10.3389/fmed.2022.866343