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Combination of Vitamin C and Curcumin Safeguards Against Methotrexate-Induced Acute Liver Injury in Mice by Synergistic Antioxidant Effects
Methotrexate (MTX), an antineoplastic and immunosuppressive drug, widely used in the treatment of different types of cancers and the management of chronic inflammatory diseases. However, its use is associated with hepatotoxicity. Vitamin C (VC) and curcumin (CUR) exhibit anti-inflammatory and antiox...
Autores principales: | Hasan Khudhair, Dhekra, Al-Gareeb, Ali I., Al-kuraishy, Hayder M., El-Kadem, Aya H., Elekhnawy, Engy, Negm, Walaa A., Saber, Sameh, Cavalu, Simona, Tirla, Adrian, Alotaibi, Saqer S., Batiha, Gaber El-Saber |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047671/ https://www.ncbi.nlm.nih.gov/pubmed/35492324 http://dx.doi.org/10.3389/fmed.2022.866343 |
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