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Non-Muscle Myosin II Is Essential for the Negative Regulation of B-Cell Receptor Signaling and B-Cell Activation

Antigen (Ag)-triggered B-cell receptor (BCR) signaling initiates antibody responses. However, prolonged or uncontrolled BCR signaling is associated with the development of self-reactive B-cells and autoimmune diseases. We previously showed that actin-mediated B-cell contraction on Ag-presenting surf...

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Detalles Bibliográficos
Autores principales: Seeley-Fallen, Margaret K., Lazzaro, Michelle, Liu, Chaohong, Li, Quan-Zhen, Upadhyaya, Arpita, Song, Wenxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047714/
https://www.ncbi.nlm.nih.gov/pubmed/35493485
http://dx.doi.org/10.3389/fimmu.2022.842605