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CCN2/CTGF—A Modulator of the Optic Nerve Head Astrocyte

In primary open-angle glaucoma (POAG), a neurodegenerative disease of the optic nerve (ON) and leading cause of blindness, the optic nerve head (ONH) undergoes marked structural extracellular matrix (ECM) changes, which contribute to its permanent deformation and to degeneration of ON axons. The rem...

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Detalles Bibliográficos
Autores principales: Dillinger, Andrea E., Weber, Gregor R., Mayer, Matthias, Schneider, Magdalena, Göppner, Corinna, Ohlmann, Andreas, Shamonin, Mikhail, Monkman, Gareth J., Fuchshofer, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047870/
https://www.ncbi.nlm.nih.gov/pubmed/35493079
http://dx.doi.org/10.3389/fcell.2022.864433