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High-Throughput Native Mass Spectrometry Screening in Drug Discovery
The design of new therapeutic molecules can be significantly informed by studying protein-ligand interactions using biophysical approaches directly after purification of the protein-ligand complex. Well-established techniques utilized in drug discovery include isothermal titration calorimetry, surfa...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047894/ https://www.ncbi.nlm.nih.gov/pubmed/35495635 http://dx.doi.org/10.3389/fmolb.2022.837901 |