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High-Throughput Native Mass Spectrometry Screening in Drug Discovery

The design of new therapeutic molecules can be significantly informed by studying protein-ligand interactions using biophysical approaches directly after purification of the protein-ligand complex. Well-established techniques utilized in drug discovery include isothermal titration calorimetry, surfa...

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Detalles Bibliográficos
Autores principales: Gavriilidou, Agni F. M., Sokratous, Kleitos, Yen, Hsin-Yung, De Colibus, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047894/
https://www.ncbi.nlm.nih.gov/pubmed/35495635
http://dx.doi.org/10.3389/fmolb.2022.837901