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Computational Site Saturation Mutagenesis of Canonical and Non-Canonical Amino Acids to Probe Protein-Peptide Interactions

Technologies for discovering peptides as potential therapeutics have rapidly advanced in recent years with significant interest from both academic and pharmaceutical labs. These advancements in turn drive the need for new computational tools to design peptides for purposes of advancing lead molecule...

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Detalles Bibliográficos
Autores principales: Holden, Jeffrey K., Pavlovicz, Ryan, Gobbi, Alberto, Song, Yifan, Cunningham, Christian N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047896/
https://www.ncbi.nlm.nih.gov/pubmed/35495632
http://dx.doi.org/10.3389/fmolb.2022.848689