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Optimization of an Intranasal Route for the Delivery of Human Neural Stem Cells to Treat a Neonatal Hypoxic-Ischemic Brain Injury Rat Model

OBJECTIVE: Stem cell administration via the intranasal route has shown promise as a new therapy for hypoxic-ischemic encephalopathy (HIE). In this study, we aimed to improve the intranasal delivery of stem cells to the brain. METHODS: Human neural stem cells (hNSCs) were identified using immunofluor...

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Detalles Bibliográficos
Autores principales: Lu, Siliang, Li, Ke, Yang, Yinxiang, Wang, Qian, Yu, Yu, Wang, Zhaoyan, Luan, Zuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047963/
https://www.ncbi.nlm.nih.gov/pubmed/35495583
http://dx.doi.org/10.2147/NDT.S350586