Purification and cryo-EM structure determination of VCP/p97 dodecamers from mammalian and bacterial cells

Valosin-containing protein (VCP, also known as p97/Cdc48) comprises six identical 97 kDa VCP protomers and functions as a master regulator of cellular homeostasis. VCP dodecamer in an apo nucleotide status was recently reported, providing a new framework for studying VCP’s diverse biological functio...

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Detalles Bibliográficos
Autores principales: Yu, Guimei, Bai, Yunpeng, Zhang, Zhong-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048083/
https://www.ncbi.nlm.nih.gov/pubmed/35496809
http://dx.doi.org/10.1016/j.xpro.2022.101339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048083/
https://www.ncbi.nlm.nih.gov/pubmed/35496809
http://dx.doi.org/10.1016/j.xpro.2022.101339

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