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Luteolin attenuates the chemoresistance of osteosarcoma through inhibiting the PTN/β-catenin/MDR1 signaling axis by upregulating miR-384

Multidrug resistance (MDR) remains a critical bottleneck in successful treatment of osteosarcoma (OS). Luteolin is a flavonoid compound that has been verified to increase the sensitivity to antineoplastic drugs in many tumors. However, its roles in reversing MDR of OS and the potential underlying me...

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Detalles Bibliográficos
Autores principales: Qin, Tao, Zhu, Wenjing, Kan, Xiaoli, Li, Ling, Wu, Dapeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048097/
https://www.ncbi.nlm.nih.gov/pubmed/35493691
http://dx.doi.org/10.1016/j.jbo.2022.100429