Cargando…

Luteolin attenuates the chemoresistance of osteosarcoma through inhibiting the PTN/β-catenin/MDR1 signaling axis by upregulating miR-384

Multidrug resistance (MDR) remains a critical bottleneck in successful treatment of osteosarcoma (OS). Luteolin is a flavonoid compound that has been verified to increase the sensitivity to antineoplastic drugs in many tumors. However, its roles in reversing MDR of OS and the potential underlying me...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qin, Tao, Zhu, Wenjing, Kan, Xiaoli, Li, Ling, Wu, Dapeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048097/ https://www.ncbi.nlm.nih.gov/pubmed/35493691 http://dx.doi.org/10.1016/j.jbo.2022.100429

Ejemplares similares

DHFR and MDR1 upregulation is associated with chemoresistance in osteosarcoma stem-like cells
por: Lee, Yu-Hsien, et al.
Publicado: (2017)

Luteolin suppresses colorectal cancer cell metastasis via regulation of the miR-384/pleiotrophin axis
por: Yao, Yuanyuan, et al.
Publicado: (2019)

miR-627-3p inhibits osteosarcoma cell proliferation and metastasis by targeting PTN
por: He, Ming, et al.
Publicado: (2019)

Pleiotrophin promotes chemoresistance to doxorubicin in osteosarcoma by upregulating P-glycoprotein
por: Wu, Dapeng, et al.
Publicado: (2017)

CD44 Contributes to the Regulation of MDR1 Protein and Doxorubicin Chemoresistance in Osteosarcoma
por: Gerardo-Ramírez, Monserrat, et al.
Publicado: (2022)

Chemotherapy-driven increases in the CDKN1A/PTN/PTPRZ1 axis promote chemoresistance by activating the NF-κB pathway in breast cancer cells
por: Huang, Peng, et al.
Publicado: (2018)

Luteolin-7-glucoside Promotes Human Epidermal Stem Cell Proliferation by Upregulating β-Catenin, c-Myc, and Cyclin Expression
por: Wan, Dapeng, et al.
Publicado: (2019)

Connecting Metainflammation and Neuroinflammation Through the PTN-MK-RPTPβ/ζ Axis: Relevance in Therapeutic Development
por: Herradon, Gonzalo, et al.
Publicado: (2019)

CircRNA-PTN Sponges miR-326 to Promote Proliferation in Hepatocellular Carcinoma
por: Jia, Benli, et al.
Publicado: (2020)

MiR-384 Inhibits Malignant Biological Behavior Such as Proliferation and Invasion of Osteosarcoma by Regulating IGFBP3
por: Tan, Yuelong, et al.
Publicado: (2020)

MicroRNA-384 inhibits nasopharyngeal carcinoma growth and metastasis via binding to Smad5 and suppressing the Wnt/β-catenin axis
por: Zeng, Xinyu, et al.
Publicado: (2021)

circ_0008285 Regulates Glioma Progression via the miR-384/HMGB1 Axis
por: Yan, Manli, et al.
Publicado: (2023)

LncRNA PITPNA‐AS1/miR‐223‐3p/PTN axis regulates malignant progression and stemness in lung squamous cell carcinoma
por: Peng, Bi‐hao, et al.
Publicado: (2022)

Role of Wnt/β-Catenin Signaling in the Chemoresistance Modulation of Colorectal Cancer
por: Yuan, Shengli, et al.
Publicado: (2020)

The Na+/K+ ATPase Inhibitor Ouabain Attenuates Stemness and Chemoresistance of Osteosarcoma Cells
por: Guo, Weixiong, et al.
Publicado: (2019)

miR-182 aids in receptive endometrium development in dairy goats by down-regulating PTN expression
por: Zhang, Lei, et al.
Publicado: (2017)

circPTN Promotes the Progression of Non-Small Cell Lung Cancer through Upregulation of E2F2 by Sponging miR-432-5p
por: Su, Jiayuan, et al.
Publicado: (2022)

Pleiotrophin (PTN) Expression and Function and in the Mouse Mammary Gland and Mammary Epithelial Cells
por: Rosenfield, Sonia M., et al.
Publicado: (2012)

A meta-analysis on the role of pleiotrophin (PTN) as a prognostic factor in cancer
por: Zhou, Jiupeng, et al.
Publicado: (2018)

Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer
por: Liu, Shiqin, et al.
Publicado: (2020)

Zinc finger protein 384 enhances colorectal cancer metastasis by upregulating MMP2
por: Yan, Zaihua, et al.
Publicado: (2022)

Overexpression of zinc finger protein 384 (ZNF 384), a poor prognostic predictor, promotes cell growth by upregulating the expression of Cyclin D1 in Hepatocellular carcinoma
por: He, Lifeng, et al.
Publicado: (2019)

Long Non-Coding RNA AGAP2-AS1/miR-628-5p/PTN Axis Modulates Proliferation, Migration, Invasion, and Apoptosis of Glioma Cells
por: Yan, Yang, et al.
Publicado: (2020)

Molecular mechanisms of chemoresistance in osteosarcoma (Review)
por: HE, HONGTAO, et al.
Publicado: (2014)

Correction: Pleiotrophin (PTN) Expression and Function in the Mouse Mammary Gland and Mammary Epithelial Cells
por: Rosenfield, Sonia M., et al.
Publicado: (2013)

CREB3L1 and PTN expressions correlate with prognosis of brain glioma patients
por: Liu, Li-qiang, et al.
Publicado: (2018)

Prevention of multidrug resistance (MDR) in osteosarcoma by NSC23925
por: Yang, X, et al.
Publicado: (2014)

Targeting the CtBP1-FOXM1 transcriptional complex with small molecules to overcome MDR1-mediated chemoresistance in osteosarcoma cancer stem cells
por: Chen, Xun, et al.
Publicado: (2021)

The miR-17-92 cluster/QKI2/β-catenin axis promotes osteosarcoma progression
por: Yang, Hongbo, et al.
Publicado: (2018)

Luteolin attenuates Wnt signaling via upregulation of FZD6 to suppress prostate cancer stemness revealed by comparative proteomics
por: Han, Kun, et al.
Publicado: (2018)

Luteolin modulates SERCA2a via Sp1 upregulation to attenuate myocardial ischemia/reperfusion injury in mice
por: Hu, Ya, et al.
Publicado: (2020)

Long Non-Coding RNA AGAP2-AS1/miR-628-5p/PTN Axis Modulates Proliferation, Migration, Invasion, and Apoptosis of Glioma Cells [Retraction]
Publicado: (2020)

Molecular Mechanisms of Luteolin Induced Growth Inhibition and Apoptosis of Human Osteosarcoma Cells
por: Wang, Yonghong, et al.
Publicado: (2015)

Luteolin attenuates endotoxin-induced uveitis in Lewis rats
por: KANAI, Kazutaka, et al.
Publicado: (2016)

Self-Renewal and Pluripotency in Osteosarcoma Stem Cells’ Chemoresistance: Notch, Hedgehog, and Wnt/β-Catenin Interplay with Embryonic Markers
por: Martins-Neves, Sara R., et al.
Publicado: (2023)

miR‑122/SENP1 axis confers stemness and chemoresistance to liver cancer through Wnt/β‑catenin signaling
por: Dai, Jianbo, et al.
Publicado: (2023)

Effects of microenvironment in osteosarcoma on chemoresistance and the promise of immunotherapy as an osteosarcoma therapeutic modality
por: Yu, Lei, et al.
Publicado: (2022)

Long non-coding RNA SNHG3 accelerates progression in glioma by modulating miR-384/HDGF axis
por: Zhang, Xiaofeng, et al.
Publicado: (2020)

circPTN sponges miR-145-5p/miR-330-5p to promote proliferation and stemness in glioma
por: Chen, Jiansheng, et al.
Publicado: (2019)

Spaceflight Influences both Mucosal and Peripheral Cytokine Production in PTN-Tg and Wild Type Mice
por: McCarville, Justin L., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_rkclvn1uj6kqdd59fp36aqbr52