Metformin overcomes metabolic reprogramming-induced resistance of skin squamous cell carcinoma to photodynamic therapy

OBJECTIVE: Cancer metabolic reprogramming promotes resistance to therapies. In this study, we addressed the role of the Warburg effect in the resistance to photodynamic therapy (PDT) in skin squamous cell carcinoma (sSCC). Furthermore, we assessed the effect of metformin treatment, an antidiabetic t...

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Detalles Bibliográficos
Autores principales: Mascaraque-Checa, Marta, Gallego-Rentero, María, Nicolás-Morala, Jimena, Portillo-Esnaola, Mikel, Cuezva, José M., González, Salvador, Gilaberte, Yolanda, Juarranz, Ángeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048115/
https://www.ncbi.nlm.nih.gov/pubmed/35405370
http://dx.doi.org/10.1016/j.molmet.2022.101496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048115/
https://www.ncbi.nlm.nih.gov/pubmed/35405370
http://dx.doi.org/10.1016/j.molmet.2022.101496

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