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Evaluation of cytotoxic potential of structurally well-characterized RNA targeted ionic non-steroidal anti-inflammatory (NSAID) Cu(ii) & Zn(ii) DACH–mefenamato drug conjugates against human cancer cell lines

New RNA targeted ionic [Cu(DACH)(2)(H(2)O)(2)](mef)(2), 1 and [Zn(DACH)(2)(H(2)O)(2)](mef)(2), 2 drug conjugates were synthesized and characterized by spectroscopic techniques FT-IR, UV-vis, EPR in case of 1 and (1)H and (13)C NMR in case of 2, ESI-MS, thermogravimetric analysis and single-crystal X...

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Detalles Bibliográficos
Autores principales: Khan, Huzaifa Yasir, Tabassum, Sartaj, Arjmand, Farukh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048248/
https://www.ncbi.nlm.nih.gov/pubmed/35492558
http://dx.doi.org/10.1039/c9ra07464c