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An early proinflammatory transcriptional response to tau pathology is age‐specific and foreshadows reduced tau burden

Age is one of the strongest risk factors for the development of neurodegenerative diseases, the majority of which involve misfolded protein aggregates in the brain. These protein aggregates are thought to drive pathology and are attractive targets for the development of new therapies. However, it is...

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Detalles Bibliográficos
Autores principales: Rasmussen, Jay, Ewing, Adam D., Bodea, Liviu‐Gabriel, Bodea, Gabriela O., Gearing, Marla, Faulkner, Geoffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048516/
https://www.ncbi.nlm.nih.gov/pubmed/34463402
http://dx.doi.org/10.1111/bpa.13018