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Functional metabolomics using UPLC-Q/TOF-MS combined with ingenuity pathway analysis as a promising strategy for evaluating the efficacy and discovering amino acid metabolism as a potential therapeutic mechanism-related target for geniposide against alcoholic liver disease

Metabolomics has been used as a promising strategy to evaluate the efficacy of and potential targets for natural products. Alcoholic liver disease (ALD) as a result of chronic ethanol consumption has high morbidity and mortality. Geniposide possesses a hepatoprotective activity against ALD, but its...

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Detalles Bibliográficos
Autores principales: Qiu, Shi, Zhang, Ai-hua, Guan, Yu, Sun, Hui, Zhang, Tian-lei, Han, Ying, Yan, Guang-li, Wang, Xi-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048633/
https://www.ncbi.nlm.nih.gov/pubmed/35496090
http://dx.doi.org/10.1039/c9ra09305b