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Transgene-design: a web application for the design of mammalian transgenes

SUMMARY: Transgene-design is a web application to help design transgenes for use in mammalian studies. It is predicated on the recent discovery that human intronless transgenes and native retrogenes can be expressed very effectively if the GC content at exonic synonymous sites is high. In addition,...

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Detalles Bibliográficos
Autores principales: Mühlhausen, Stefanie, Hurst, Laurence D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048660/
https://www.ncbi.nlm.nih.gov/pubmed/35244144
http://dx.doi.org/10.1093/bioinformatics/btac139