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AbDiver: a tool to explore the natural antibody landscape to aid therapeutic design

MOTIVATION: Rational design of therapeutic antibodies can be improved by harnessing the natural sequence diversity of these molecules. Our understanding of the diversity of antibodies has recently been greatly facilitated through the deposition of hundreds of millions of human antibody sequences in...

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Detalles Bibliográficos
Autores principales: Młokosiewicz, Jakub, Deszyński, Piotr, Wilman, Wiktoria, Jaszczyszyn, Igor, Ganesan, Rajkumar, Kovaltsuk, Aleksandr, Leem, Jinwoo, Galson, Jacob D, Krawczyk, Konrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048670/
https://www.ncbi.nlm.nih.gov/pubmed/35274671
http://dx.doi.org/10.1093/bioinformatics/btac151