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AbDiver: a tool to explore the natural antibody landscape to aid therapeutic design
MOTIVATION: Rational design of therapeutic antibodies can be improved by harnessing the natural sequence diversity of these molecules. Our understanding of the diversity of antibodies has recently been greatly facilitated through the deposition of hundreds of millions of human antibody sequences in...
Autores principales: | Młokosiewicz, Jakub, Deszyński, Piotr, Wilman, Wiktoria, Jaszczyszyn, Igor, Ganesan, Rajkumar, Kovaltsuk, Aleksandr, Leem, Jinwoo, Galson, Jacob D, Krawczyk, Konrad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048670/ https://www.ncbi.nlm.nih.gov/pubmed/35274671 http://dx.doi.org/10.1093/bioinformatics/btac151 |
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