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POIBM: batch correction of heterogeneous RNA-seq datasets through latent sample matching
MOTIVATION: RNA sequencing and other high-throughput technologies are essential in understanding complex diseases, such as cancers, but are susceptible to technical factors manifesting as patterns in the measurements. These batch patterns hinder the discovery of biologically relevant patterns. Unbia...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048693/ https://www.ncbi.nlm.nih.gov/pubmed/35199138 http://dx.doi.org/10.1093/bioinformatics/btac124 |