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Synthesis of new oxadiazol-phthalazinone derivatives with anti-proliferative activity; molecular docking, pro-apoptotic, and enzyme inhibition profile

Background and aim: The current study reports the synthesis and biological evaluation of two novel series of 4-(5-mercapto-1,3,4-oxadiazol-2-yl)phthalazin-1(2H)-one derivatives. Methods: The synthetic reactions were carried out under both conventional and ultrasonic irradiation conditions. The anti-...

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Detalles Bibliográficos
Autores principales:	Hekal, Mohamed H., El-Naggar, Abeer M., Abu El-Azm, Fatma S. M., El-Sayed, Wael M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048702/ https://www.ncbi.nlm.nih.gov/pubmed/35492649 http://dx.doi.org/10.1039/c9ra09016a

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