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Synthesis of cucurbitacin IIa derivatives with apoptosis-inducing capabilities in human cancer cells
Twenty-one cucurbitacin IIa derivatives were synthesized and screened for cytotoxic activity. Their structures were established using (1)H NMR, (13)C NMR, and LC-MS spectroscopic data. The absolute configuration of the derivatives was determined by single crystal diffraction. In sulforhodamine B (SR...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048769/ https://www.ncbi.nlm.nih.gov/pubmed/35492669 http://dx.doi.org/10.1039/c9ra09113k |