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Synthesis of cucurbitacin IIa derivatives with apoptosis-inducing capabilities in human cancer cells

Twenty-one cucurbitacin IIa derivatives were synthesized and screened for cytotoxic activity. Their structures were established using (1)H NMR, (13)C NMR, and LC-MS spectroscopic data. The absolute configuration of the derivatives was determined by single crystal diffraction. In sulforhodamine B (SR...

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Detalles Bibliográficos
Autores principales:	Yu, Kun, Yang, Xinmei, Li, Ying, Cui, Xue, Liu, Bo, Yao, Qingqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048769/ https://www.ncbi.nlm.nih.gov/pubmed/35492669 http://dx.doi.org/10.1039/c9ra09113k

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