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Variability in the type and layer distribution of cortical Aβ pathology in familial Alzheimer’s disease

Familial Alzheimer's disease (FAD) is caused by autosomal dominant mutations in the PSEN1, PSEN2 or APP genes, giving rise to considerable clinical and pathological heterogeneity in FAD. Here we investigate variability in clinical data and the type and distribution of Aβ pathologies throughout...

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Detalles Bibliográficos
Autores principales: Willumsen, Nanet, Poole, Teresa, Nicholas, Jennifer M., Fox, Nick C., Ryan, Natalie S., Lashley, Tammaryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048809/
https://www.ncbi.nlm.nih.gov/pubmed/34319632
http://dx.doi.org/10.1111/bpa.13009