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Efficient synthesis of 1-iodoalkynes via Al(2)O(3) mediated reaction of terminal alkynes and N-iodosuccinimide
Iodination of terminal alkynes using N-iodosuccinimide (NIS) in the presence of γ-Al(2)O(3) was developed to afford 1-iodoalkynes with good to excellent yields (up to 99%). This described approach featured excellent chemoselectivity, good functional group tolerance, and utilization of an inexpensive...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048840/ https://www.ncbi.nlm.nih.gov/pubmed/35492642 http://dx.doi.org/10.1039/d0ra00251h |