Effects of a natural PTP1B inhibitor from Rhodomela confervoides on the amelioration of fatty acid-induced insulin resistance in hepatocytes and hyperglycaemia in STZ-induced diabetic rats

PTP1B is a key negative regulator of insulin signaling transduction, and the inhibition of PTP1B has emerged as a potential therapeutic strategy to treat T2DM. 3,4-Dibromo-5-(2-bromo-6-(ethoxymethyl)-3,4-dihydroxybenzyl)benzene-1,2-diol (BPN), a natural bromophenol isolated from marine red alga Rhod...

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Detalles Bibliográficos
Autores principales: Guo, Shuju, Wang, Lijun, Chen, Dong, Jiang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048848/
https://www.ncbi.nlm.nih.gov/pubmed/35497760
http://dx.doi.org/10.1039/c9ra10660j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048848/
https://www.ncbi.nlm.nih.gov/pubmed/35497760
http://dx.doi.org/10.1039/c9ra10660j

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