Phylogeny-Aware Chemoinformatic Analysis of Chemical Diversity in Lamiaceae Enables Iridoid Pathway Assembly and Discovery of Aucubin Synthase

Countless reports describe the isolation and structural characterization of natural products, yet this information remains disconnected and underutilized. Using a cheminformatics approach, we leverage the reported observations of iridoid glucosides with the known phylogeny of a large iridoid produci...

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Detalles Bibliográficos
Autores principales: Rodríguez-López, Carlos E., Jiang, Yindi, Kamileen, Mohamed O., Lichman, Benjamin R., Hong, Benke, Vaillancourt, Brieanne, Buell, C. Robin, O'Connor, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048965/
https://www.ncbi.nlm.nih.gov/pubmed/35298643
http://dx.doi.org/10.1093/molbev/msac057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048965/
https://www.ncbi.nlm.nih.gov/pubmed/35298643
http://dx.doi.org/10.1093/molbev/msac057

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