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Phylogeny-Aware Chemoinformatic Analysis of Chemical Diversity in Lamiaceae Enables Iridoid Pathway Assembly and Discovery of Aucubin Synthase
Countless reports describe the isolation and structural characterization of natural products, yet this information remains disconnected and underutilized. Using a cheminformatics approach, we leverage the reported observations of iridoid glucosides with the known phylogeny of a large iridoid produci...
Autores principales: | Rodríguez-López, Carlos E., Jiang, Yindi, Kamileen, Mohamed O., Lichman, Benjamin R., Hong, Benke, Vaillancourt, Brieanne, Buell, C. Robin, O'Connor, Sarah E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048965/ https://www.ncbi.nlm.nih.gov/pubmed/35298643 http://dx.doi.org/10.1093/molbev/msac057 |
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