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pH-sensitive CAP/SiO(2) composite for efficient co-delivery of doxorubicin and siRNA to overcome multiple drug resistance
Long-term administration of chemotherapeutic agents often leads to multiple drug resistance (MDR), which greatly impairs the treatment outcome. To overcome this problem, a biodegradable nanocarrier based on an acid-sensitive calcium phosphate/silica dioxide (CAP/SiO(2)) composite was constructed for...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049068/ https://www.ncbi.nlm.nih.gov/pubmed/35495266 http://dx.doi.org/10.1039/c9ra07894k |