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pH-sensitive CAP/SiO(2) composite for efficient co-delivery of doxorubicin and siRNA to overcome multiple drug resistance

Long-term administration of chemotherapeutic agents often leads to multiple drug resistance (MDR), which greatly impairs the treatment outcome. To overcome this problem, a biodegradable nanocarrier based on an acid-sensitive calcium phosphate/silica dioxide (CAP/SiO(2)) composite was constructed for...

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Detalles Bibliográficos
Autores principales: Cai, Zheng, Chen, Yuezhu, Zhang, Yingwen, He, Zhimei, Wu, Xiaoge, Jiang, Li-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049068/
https://www.ncbi.nlm.nih.gov/pubmed/35495266
http://dx.doi.org/10.1039/c9ra07894k