Regioselective convergent synthesis of 2-arylidene thiazolo[3,2-a]pyrimidines as potential anti-chikungunya agents

Convergent and convenient regioselective synthesis of novel thiazolo[2,3-a]pyrimidine derivatives was accomplished using the one-pot reaction of 6-ethylthiouracil, bromoacetic acid, anhydrous sodium acetate, acetic anhydride, acetic acid and suitable aldehyde. X-ray crystallographic study reveals th...

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Detalles Bibliográficos
Autores principales: Fares, Mohamed, McCosker, Patrick M., Alsherbiny, Muhammad A., Willis, Anthony C., Clark, Timothy, Neyts, Johan, Jochmans, Dirk, Keller, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049071/
https://www.ncbi.nlm.nih.gov/pubmed/35498334
http://dx.doi.org/10.1039/d0ra00257g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049071/
https://www.ncbi.nlm.nih.gov/pubmed/35498334
http://dx.doi.org/10.1039/d0ra00257g

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