Cell-Free DNA Promotes Inflammation in Patients With Oral Lichen Planus via the STING Pathway

BACKGROUND: Damaged and dead cells release cell-free DNA (cfDNA) that activates cyclic GMP–AMP (cGAMP) synthase (cGAS), which leads to the activation of stimulator of interferon genes (STING) via the second messenger cGAMP. STING promotes the production of inflammatory cytokines and type I interfero...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Jing, Pan, Weiyi, Ji, Ning, Liu, Na, Chen, Qian, Chen, Jinhuan, Sun, Yutong, Xie, Liang, Chen, Qianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049180/
https://www.ncbi.nlm.nih.gov/pubmed/35493447
http://dx.doi.org/10.3389/fimmu.2022.838109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049180/
https://www.ncbi.nlm.nih.gov/pubmed/35493447
http://dx.doi.org/10.3389/fimmu.2022.838109

Ejemplares similares