Tryptophan promoted β-defensin-2 expression via the mTOR pathway and its metabolites: kynurenine banding to aryl hydrocarbon receptor in rat intestine

In this study, we investigated the signalling pathways mediating tryptophan (Trp)-promoted β-defensin-2 (BD-2) expression in rat intestinal mucosa. Sprague Dawley rats were administered with l-Trp and treated with rapamycin (RAPA), 1-methyltryptophan (1-MT), or para-chlorophenyl-amine (PCPA) to inhi...

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Detalles Bibliográficos
Autores principales: Tang, Zhiru, Shi, Baoshi, Sun, Weizhong, Yin, Yulong, Chen, Qingju, Mohamed, Taha, Lu, Changwen, Sun, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049194/
https://www.ncbi.nlm.nih.gov/pubmed/35497743
http://dx.doi.org/10.1039/c9ra10477a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049194/
https://www.ncbi.nlm.nih.gov/pubmed/35497743
http://dx.doi.org/10.1039/c9ra10477a

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