Imaging the influence of peripheral TRPV1-signaling on cerebral nociceptive processing applying fMRI-based graph theory in a resiniferatoxin rat model

Resiniferatoxin (RTX), an extract from the spurge plant Euphorbia resinifera, is a potent agonist of the transient receptor potential cation channel subfamily V member 1 (TRPV1), mainly expressed on peripheral nociceptors—a prerequisite for nociceptive heat perception. Systemic overdosing of RTX can...

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Detalles Bibliográficos
Autores principales: Wank, Isabel, Kutsche, Lisa, Kreitz, Silke, Reeh, Peter, Hess, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049522/
https://www.ncbi.nlm.nih.gov/pubmed/35482725
http://dx.doi.org/10.1371/journal.pone.0266669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049522/
https://www.ncbi.nlm.nih.gov/pubmed/35482725
http://dx.doi.org/10.1371/journal.pone.0266669

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