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Engineered EryF hydroxylase improving heterologous polyketide erythronolide B production in Escherichia coli
In the last two decades, the production of complex polyketides such as erythromycin and its precursor 6‐deoxyerythronolide B (6‐dEB) was demonstrated feasible in Escherichia coli. Although the heterologous production of polyketide skeleton 6‐dEB has reached 210 mg l(−1) in E. coli, the yield of its...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049603/ https://www.ncbi.nlm.nih.gov/pubmed/35174640 http://dx.doi.org/10.1111/1751-7915.14000 |